DERMATOSIS CENICIENTA PDF

Dajora You can change the settings or obtain more information by clicking here. The etiology of EDP is unknown. Erythema dyschromicum dermatosiz is most common in Latin America and Asia; most of the cases occur dermatosis cenicienta El Salvador where the first case was identified. Are you a health professional able to prescribe or dispense drugs? One case may be particularly revealing, that of a year-old rural northern European truant who repeatedly ingested small amounts of a fertilizer, ammonium nitrate, to induce EDP and avoid school. Previous article Next article.

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Abstract Objective Erythema dyschromicum perstans EDP can be difficult to diagnose and treat; therefore, we reviewed the literature to assess whether histology can be used to differentiate lichen planus pigmentosus LPP from EDP and determine which treatments are the most effective for EDP. Methods A systematic review in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses was conducted up to July using four databases.

Results Histologic analyses from the literature reveal a significant percentage of melanophages, lymphocytic infiltrates, and basal vacuolar degeneration in EDP, and a significant histologic overlap with LPP.

The review of the literature on treatment outcomes showed that NB-UVB and tacrolimus were effective with minimal side effects. Clofazimine was effective, but demonstrated significant-to-intolerable side effects. Griseofulvin, isotretinoin, and dapsone provided unsatisfactory results as lesions recurred after discontinuation. Lasers were largely ineffective and may cause postinflammatory hyperpigmentation and fibrosis. Conclusion A diagnosis of EDP should not be based on histologic findings alone.

Larger studies are needed to confirm these findings. Keywords: Erythema dyschromicum perstans, ashy dermatosis, hyperpigmentation, narrow-band UVB, lichen planus pigmentosus, post-inflammatory hyperpigmentation Introduction Erythema dyschromicum perstans EDP is a disorder of pigmentation that is characterized by gray or blue-brown macules or patches in individuals with Fitzpatrick skin types III-V Chang et al.

The lesions are usually distributed symmetrically on both sun- and non-sun-exposed areas including the trunk EDP is a chronic progressive disorder that can present similarly to several other pigmentation disorders, such as lichen planus pigmentosus LPP , and thereby result in difficulties to establish a diagnosis and treatment Cutri et al.

On histology, a vacuolar liquefactive degeneration of the basal cell layer with dermal melanosis and a perivascular infiltrate was observed. This condition was later named ashy dermatosis. In , Convit et al. These authors named this condition EDP, with an emphasis on the erythematous margin of the active lesions. Since then, several authors have attempted to determine whether EDP is a unique entity or within a spectrum of other dyschromias, such as LPP Bhutani, , Ghosh and Coondoo, Overall, there is now consensus that EDP and ashy dermatosis refer to different stages of the same condition Zaynoun et al.

The exact etiology of EDP is unknown. A genetic susceptibility conferred by genes located in the major histocompatibility complex mostly HLA-DR4 has also been described Correa et al. In one study, patch testing was used to identify possible triggers of EDP and other dyschromias, such as LPP and pigmented contact dermatitis.

Despite the growing body of literature on EDP since , there are no treatments that are consistently effective Combemale et al. In our case report, we describe a patient with EDP who was successfully treated using narrow-band ultraviolet B NB-UVB with sustained resolution at a long-term follow up of 4 years.

In our systematic review, we investigate whether histology can be used to differentiate LPP from EDP, and summarize reported treatment outcomes and side effects. Case report We report the case of a year-old male patient with Fitzpatrick skin type IV who had a 1.

Oral and nasal mucosa as well as the palms, soles, scalp, and nails were normal. A diagnosis of EDP was made by using the following clinical and histopathologic criteria: i eruption of multiple blue-gray macules or patches in typical distribution; ii histopathologically compatible with EDP; and iii absence of pigmentation-related, underlying diseases and drug history. There was no history of similar skin lesions and no personal or family history of autoimmune diseases or thyroid disease.

The patient was otherwise a healthy man with no history of sexually transmitted diseases, medications, long-term use of cosmetics, or other topical products to the skin. He also did not have any history of photosensitivity or worsening skin lesions with natural sun exposure. A skin biopsy was performed and the test results indicated mild interface dermatitis with dermal melanophages Fig.

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Dermatitis cenicienta

Abstract Objective Erythema dyschromicum perstans EDP can be difficult to diagnose and treat; therefore, we reviewed the literature to assess whether histology can be used to differentiate lichen planus pigmentosus LPP from EDP and determine which treatments are the most effective for EDP. Methods A systematic review in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses was conducted up to July using four databases. Results Histologic analyses from the literature reveal a significant percentage of melanophages, lymphocytic infiltrates, and basal vacuolar degeneration in EDP, and a significant histologic overlap with LPP. The review of the literature on treatment outcomes showed that NB-UVB and tacrolimus were effective with minimal side effects. Clofazimine was effective, but demonstrated significant-to-intolerable side effects.

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